A. Lemere, Cynthia: search on Z-Library

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1

The epigenetics of aging and neurodegeneration

Lardenoije, Roy, Iatrou, Artemis, Kenis, Gunter, Kompotis, Konstantinos, Steinbusch, Harry W.M., Mastroeni, Diego, Coleman, Paul, Lemere, Cynthia A., Hof, Patrick R., van den Hove, Daniel L.A., Rutten

Journal:

Progress in Neurobiology

Year:

2015

Language:

english

File:

PDF, 8.64 MB

english, 2015

2

Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

Shankar, Ganesh M, Li, Shaomin, Mehta, Tapan H, Garcia-Munoz, Amaya, Shepardson, Nina E, Smith, Imelda, Brett, Francesca M, Farrell, Michael A, Rowan, Michael J, Lemere, Cynthia A

Journal:

Nature Medicine

Year:

2008

Language:

english

File:

PDF, 316 KB

english, 2008

3

P1-417: How does elimination of TNF receptor affect amyloid-β protein generation and prevent learning and memory deficits in transgenic Alzheimer's mice?

Shen, Yong, He, Ping, Zhong, Jason, Lindholm, Kristina, Arnold, Gina, Lee, Wendy, Ciavarella, Gina, Lemere, Cynthia, Staufenbiel, Matthias, Li, Rena

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 70 KB

english, 2008

4

Deposition of phosphorylated amyloid-β in brains of aged nonhuman primates and canines

Kumar, Sathish, Frost, Jeffrey L., Cotman, Carl W., Head, Elizabeth, Palmour, Roberta, Lemere, Cynthia A., Walter, Jochen

Journal:

Brain Pathology

Year:

2018

Language:

english

File:

PDF, 300 KB

english, 2018

5

Aging in Down Syndrome and the Development of Alzheimer's Disease Neuropathology

Head, Elizabeth, T. Lott, Ira, M. Wilcock, Donna, A. Lemere, Cynthia

Journal:

Current Alzheimer Research

Year:

2015

Language:

english

File:

PDF, 526 KB

english, 2015

6

Scientific Advising and Reviewing: On strengthening the bond between the Alzheimer's Association and the scientific community

Knopman, David, Lemere, Cynthia A., Lamb, Bruce T., Craft, Suzanne, Gitlin, Laura N., Golde, Todd E., PericakâVance, Margaret, Sano, Mary, Schellenberg, Gerard, Schneider, Julie A., Zheng, Hui, Khac

Journal:

Alzheimer's & Dementia

Year:

2020

File:

PDF, 99 KB

2020

7

Rapid activity-dependent sprouting of optic fibers into a local area denervated by application of beta-bungarotoxin in goldfish tectum

John T. Schmidt, Cynthia A. Lemere

Journal:

Developmental Neurobiology

Year:

1996

Language:

english

File:

PDF, 1.42 MB

english, 1996

8

Nasal administration of amyloid-β peptide decreases cerebral amyloid burden in a mouse model of Alzheimer's disease

Howard L. Weiner, Cynthia A. Lemere, Ruth Maron, Edward T. Spooner, Trelawney J. Grenfell, Chica Mori, Shohreh Issazadeh, Wayne W. Hancock, Dennis J. Selkoe

Journal:

Annals of Neurology

Year:

2000

Language:

english

File:

PDF, 2.66 MB

english, 2000

9

Minocycline affects microglia activation, Aβ deposition, and behavior in APP-tg mice

Timothy J. Seabrook, Liying Jiang, Marcel Maier, Cynthia A. Lemere

Journal:

Year:

2006

Language:

english

File:

PDF, 300 KB

english, 2006

10

Effects of huperzine A on amyloid precursor protein processing and β-amyloid generation in human embryonic kidney 293 APP Swedish mutant cells

Ying Peng, Liying Jiang, David Y.W. Lee, Steven C. Schachter, Zhongze Ma, Cynthia A. Lemere

Journal:

Journal of Neuroscience Research

Year:

2006

Language:

english

File:

PDF, 269 KB

english, 2006

11

Increased DJ-1 expression under oxidative stress and in Alzheimer's disease brains

Stéphanie Baulac, Hope Lu, Jennifer Strahle, Ting Yang, Matthew S Goldberg, Jie Shen, Michael G Schlossmacher, Cynthia A Lemere, Qun Lu, Weiming Xia

Journal:

Molecular Neurodegeneration

Year:

2009

Language:

english

File:

PDF, 3.14 MB

english, 2009

12

Characterization of Aβ11-40/42 peptide deposition in Alzheimer’s disease and young Down’s syndrome brains: implication of N-terminally truncated Aβ species in the pathogenesis of Alzheimer’s disease

Kangning Liu, Ingrid Solano, David Mann, Cynthia Lemere, Marc Mercken, John Q. Trojanowski, Virginia M.-Y. Lee

Journal:

Acta Neuropathologica

Year:

2006

Language:

english

File:

PDF, 770 KB

english, 2006

13

Preferential labeling of Alzheimer neurofibrillary tangles with antisera for tau protein kinase (TPK) I/glycogen synthase kinase-3β and cyclin-dependent kinase 5, a component of TPK II

Haruyasu Yamaguchi, Koichi Ishiguro, Tsuneko Uchida, Akihiko Takashima, Cynthia A. Lemere, K. Imahori

Journal:

Acta Neuropathologica

Year:

1996

Language:

english

File:

PDF, 2.71 MB

english, 1996

14

Regional distribution of TDP-43 inclusions in Alzheimer disease (AD) brains: Their relation to AD common pathology

Ai Kadokura, Tsuneo Yamazaki, Cynthia A. Lemere, Masamitsu Takatama, Koichi Okamoto

Journal:

Year:

2009

Language:

english

File:

PDF, 579 KB

english, 2009

15

The E280A presenilin 1 Alzheimer mutation produces increased Aβ42 deposition and severe cerebellar pathology

Lemere, Cynthia A., Lopera, Francisco, Kosik, Kenneth S., Lendon, Corrine L., Ossa, Jorge, Saido, Takaomi C., Yamaguchi, Haruyasu, Ruiz, Andres, Martinez, Alonso, Madrigal, Lucia

Journal:

Nature Medicine

Year:

1996

File:

PDF, 809 KB

1996

16

Amyloid β protein immunotherapy neutralizes Aβ oligomers that disrupt synaptic plasticity in vivo

Klyubin, Igor, Walsh, Dominic M, Lemere, Cynthia A, Cullen, William K, Shankar, Ganesh M, Betts, Vicki, Spooner, Edward T, Jiang, Liying, Anwyl, Roger, Selkoe, Dennis J

Journal:

Nature Medicine

Year:

2005

Language:

english

File:

PDF, 486 KB

english, 2005

17

The Swedish mutation causes early-onset Alzheimer's disease by β-secretase cleavage within the secretory pathway

Haass, Christian, Lemere, Cynthia A., Capell, Anja, Citron, Martin, Seubert, Peter, Schenk, Dale, Lannfelt, Lars, Selkoe, Dennis J.

Journal:

Nature Medicine

Year:

1995

File:

PDF, 865 KB

1995

18

Amyloid-Beta Immunization in Alzheimer's Disease Transgenic Mouse Models and Wildtype Mice

Cynthia A. Lemere, Edward T. Spooner, Jodi F. Leverone, Chica Mori, Melitza Iglesias, Jeanne K. Bloom, Timothy J. Seabrook

Journal:

Neurochemical Research

Year:

2003

Language:

english

File:

PDF, 1.29 MB

english, 2003

19

Complement component C3 and complement receptor type 3 contribute to the phagocytosis and clearance of fibrillar Aβ by microglia

Hongjun Fu, Bin Liu, Jeffrey L. Frost, Soyon Hong, Ming Jin, Beth Ostaszewski, Ganesh M. Shankar, Isabel M. Costantino, Michael C. Carroll, Tanya N. Mayadas, Cynthia A. Lemere

Journal:

Year:

2012

Language:

english

File:

PDF, 1.84 MB

english, 2012

20

l-3-n-butylphthalide improves cognitive impairment induced by intracerebroventricular infusion of amyloid-β peptide in rats

Ying Peng, Changhong Xing, Shaofeng Xu, Cynthia A. Lemere, Guiquan Chen, Bin Liu, Ling Wang, Yipu Feng, Xiaoliang Wang

Journal:

European Journal of Pharmacology

Year:

2009

Language:

english

File:

PDF, 518 KB

english, 2009

21

Alzheimer’s Aβ vaccination of rhesus monkeys (Macaca mulatta)

Sam Gandy, Ron B DeMattos, Cynthia A Lemere, Frank L Heppner, Jodi Leverone, Adriano Aguzzi, William B Ershler, Jinlu Dai, Paul Fraser, Peter St George Hyslop, David M Holtzman, Lary C Walker, Evan T

Journal:

Mechanisms of Ageing and Development

Year:

2004

Language:

english

File:

PDF, 52 KB

english, 2004

22

Biochemical and immunohistochemical analysis of an Alzheimer's disease mouse model reveals the presence of multiple cerebral Aβ assembly forms throughout life

Ganesh M. Shankar, Malcolm A. Leissring, Anthony Adame, Xiaoyan Sun, Edward Spooner, Eliezer Masliah, Dennis J. Selkoe, Cynthia A. Lemere, Dominic M. Walsh

Journal:

Neurobiology of Disease

Year:

2009

Language:

english

File:

PDF, 1.20 MB

english, 2009

23

Cytosolic Phospholipase A2(cPLA2) Immunoreactivity Is Elevated in Alzheimer's Disease Brain

Diane T. Stephenson, Cynthia A. Lemere, Dennis J. Selkoe, James A. Clemens

Journal:

Neurobiology of Disease

Year:

1996

Language:

english

File:

PDF, 405 KB

english, 1996

24

l-3-n-Butylphthalide ameliorates β-amyloid-induced neuronal toxicity in cultured neuronal cells

Ying Peng, Changhong Xing, Cynthia A. Lemere, Guiquan Chen, Ling Wang, Yipu Feng, Xiaoliang Wang

Journal:

Neuroscience Letters

Year:

2008

Language:

english

File:

PDF, 775 KB

english, 2008

25

Phosphorylation-dependent TDP-43 antibody detects intraneuronal dot-like structures showing morphological characters of granulovacuolar degeneration

Ai Kadokura, Tsuneo Yamazaki, Satoko Kakuda, Kouki Makioka, Cynthia A. Lemere, Yukio Fujita, Masamitsu Takatama, Koichi Okamoto

Journal:

Neuroscience Letters

Year:

2009

Language:

english

File:

PDF, 790 KB

english, 2009

26

Species-specific immune response to immunization with human versus rodent Aβ peptide

Timothy J Seabrook, Jeanne K Bloom, Melitza Iglesias, Edward T Spooner, Dominic M Walsh, Cynthia A Lemere

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 325 KB

english, 2004

27

Dendrimeric Aβ1–15 is an effective immunogen in wildtype and APP-tg mice

Timothy J. Seabrook, Katelyn Thomas, Liying Jiang, Jeanne Bloom, Edward Spooner, Marcel Maier, Gal Bitan, Cynthia A. Lemere

Journal:

Neurobiology of Aging

Year:

2007

Language:

english

File:

PDF, 656 KB

english, 2007

28

Differences in the immune response to long term Aβ vaccination in C57BL/6 and B6D2F1 mice

Timothy J. Seabrook, Melitza Iglesias, Jeanne K. Bloom, Edward T. Spooner, Cynthia A. Lemere

Journal:

Year:

2004

Language:

english

File:

PDF, 199 KB

english, 2004

29

Modulation of the humoral and cellular immune response in Aβ immunotherapy by the adjuvants monophosphoryl lipid A (MPL), cholera toxin B subunit (CTB) and E. coli enterotoxin LT(R192G)

Marcel Maier, Timothy J. Seabrook, Cynthia A. Lemere

Journal:

Year:

2005

Language:

english

File:

PDF, 480 KB

english, 2005

30

Alzheimer's Disease Aβ Vaccine Reduces Central Nervous System Aβ Levels in a Non-Human Primate, the Caribbean Vervet

Cynthia A. Lemere, Amy Beierschmitt, Melitza Iglesias, Edward T. Spooner, Jeanne K. Bloom, Jodi F. Leverone, Jessica B. Zheng, Timothy J. Seabrook, Dora Louard, Diana Li, Dennis J. Selkoe, Roberta M.

Journal:

The American Journal of Pathology

Year:

2004

Language:

english

File:

PDF, 1.35 MB

english, 2004

31

Inflammatory Responses to Amyloidosis in a Transgenic Mouse Model of Alzheimer’s Disease

Yasuji Matsuoka, Melanie Picciano, Brian Malester, John LaFrancois, Cindy Zehr, JoAnna M. Daeschner, John A. Olschowka, Maria I. Fonseca, M. Kerry O’Banion, Andrea J. Tenner, Cynthia A. Lemere, Karen

Journal:

The American Journal of Pathology

Year:

2001

Language:

english

File:

PDF, 2.29 MB

english, 2001

32

Temporal Accrual of Complement Proteins in Amyloid Plaques in Down's Syndrome with Alzheimer's Disease

Sarah E. Stoltzner, Trelawney J. Grenfell, Chica Mori, Krystyna E. Wisniewski, Thomas M. Wisniewski, Dennis J. Selkoe, Cynthia A. Lemere

Journal:

The American Journal of Pathology

Year:

2000

Language:

english

File:

PDF, 1.94 MB

english, 2000

33

The AMY Antigen Co-Occurs with Aβ and Follows Its Deposition in the Amyloid Plaques of Alzheimer's Disease and Down Syndrome

Cynthia A. Lemere, Trelawney J. Grenfell, Dennis J. Selkoe

Journal:

The American Journal of Pathology

Year:

1999

Language:

english

File:

PDF, 2.06 MB

english, 1999

34

Nasal Aβ immunization reduces amyloid-β protein burden in PDAPP mice

Cynthia A. Lemere, Ruth Maron, Edward T. Spooner, Trelawney J. Grenfell, Chica Mori, Dennis J. Selkoe

Journal:

Neurobiology of Aging

Year:

2000

Language:

english

File:

PDF, 168 KB

english, 2000

35

Intraneuronal Aβ42 immunoreactivity is inversely correlated with Alzheimer's disease pathology in down syndrome brain: A temporal study

Chica Mori, Krystyna Wisniewski, Thomas Wisniewski, Takaomi C. Saido, Dennis J. Selkoe, Cynthia A. Lemere

Journal:

Neurobiology of Aging

Year:

2000

Language:

english

File:

PDF, 197 KB

english, 2000

36

Intranasal immunotherapy for the treatment of Alzheimer’s disease: Escherichia coli LT and LT(R192G) as mucosal adjuvants

Cynthia A Lemere, Edward T Spooner, Jodi F Leverone, Chica Mori, John.D Clements

Journal:

Neurobiology of Aging

Year:

2002

Language:

english

File:

PDF, 344 KB

english, 2002

37

The generation and characterization of potentially therapeutic Aβ antibodies in mice: differences according to strain and immunization protocol

Edward T Spooner, Roanak V Desai, Chica Mori, Jodi F Leverone, Cynthia A Lemere

Journal:

Year:

2002

Language:

english

File:

PDF, 298 KB

english, 2002

38

Aβ1-15 is less immunogenic than Aβ1-40/42 for intranasal immunization of wild-type mice but may be effective for “boosting”

Jodi F. Leverone, Edward T. Spooner, Herman K. Lehman, John D. Clements, Cynthia A. Lemere

Journal:

Year:

2003

Language:

english

File:

PDF, 469 KB

english, 2003

39

Localization of flotillins in human brain and their accumulation with the progression of Alzheimer's disease pathology

Hideko Kokubo, Cynthia A Lemere, Haruyasu Yamaguchi

Journal:

Neuroscience Letters

Year:

2000

Language:

english

File:

PDF, 651 KB

english, 2000

40

Evidence for peripheral clearance of cerebral Aβ protein following chronic, active Aβ immunization in PSAPP mice

Cynthia A Lemere, Edward T Spooner, John LaFrancois, Brian Malester, Chica Mori, Jodi F Leverone, Yasuji Matsuoka, Jennie W Taylor, Ronald B DeMattos, David M Holtzman, John D Clements, Dennis J Selko

Journal:

Neurobiology of Disease

Year:

2003

Language:

english

File:

PDF, 459 KB

english, 2003

41

S1-02-01: Active Aβ vaccines stabilize or improve cognition and lower plaque burden in aged Caribbean vervets

Cynthia A. Lemere

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 58 KB

english, 2008

42

O2-02-02: Soluble amyloid β-protein dimers isolated directly from Alzheimer's disease patients potently impair synaptic plasticity and memory

Ganesh M. Shankar, Shaomin Li, Tapan H. Mehta, Amaya Garcia-Munoz, Nina E. Shepardson, Imelda Smith, Francesca M. Brett, Michael A. Farrell, Michael J. Rowan, Cynthia A. Lemere, Ciaran M. Regan, Domin

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 56 KB

english, 2008

43

Pyroglutamate 3 Abeta immunoreactivity in brains of mice, monkeys and humans

Cynthia A. Lemere, Eva M. Luo, Jeffrey L. Frost, Roberta M. Palmour, Frank R. Ervin, Keith G. Mansfield, Susan V. Westmoreland, Takaomi C. Saido, Hans-Ulrich Demuth

Journal:

Alzheimer's & Dementia

Year:

2009

Language:

english

File:

PDF, 44 KB

english, 2009

44

Aging, biomarkers and behavior in Caribbean vervets

Cynthia A. Lemere, Jeffrey L. Frost, Ilan Djivre, David Butler, Kevin Le, Maurice Matthew, Eva Luo, Anne M. Fagan, Frank R. Ervin, Roberta M. Palmour

Journal:

Alzheimer's & Dementia

Year:

2010

Language:

english

File:

PDF, 44 KB

english, 2010

45

Active immunization against pyroGlu-3 Aβ generates high antibody titers and lowers plaque burden in APP transgenic mice

Cynthia A Lemere, Jeffrey Frost, Martin Kleinschmidt, Bin Liu, Qiaoqiao Shi, Hans-Ulrich Demuth, Stephan Schilling

Journal:

Alzheimer's & Dementia

Year:

2011

Language:

english

File:

PDF, 48 KB

english, 2011

46

Boosting with intranasal dendrimeric Aβ1–15 but not Aβ1–15 peptide leads to an effective immune response following a single injection of Aβ1–40/42 in APP-tg mice

Timothy J Seabrook, Liying Jiang, Katelyn Thomas, Cynthia A Lemere

Journal:

Journal of Neuroinflammation

Year:

2006

Language:

english

File:

PDF, 675 KB

english, 2006

47

Osteopetrotic (op/op) mice have reduced microglia, no Aβ deposition, and no changes in dopaminergic neurons

Yoichi Kondo, Cynthia A Lemere, Timothy J Seabrook

Journal:

Journal of Neuroinflammation

Year:

2007

Language:

english

File:

PDF, 1.48 MB

english, 2007

48

Developing Novel Immunogens for an Effective, Safe Alzheimer’s Disease Vaccine

Maier, Marcel, Seabrook, Timothy J., Lemere, Cynthia A.

Journal:

Neurodegenerative Diseases

Year:

2005

Language:

english

File:

PDF, 171 KB

english, 2005

49

Immunotherapy for Alzheimer’s disease: hoops and hurdles

Lemere, Cynthia A

Journal:

Molecular Neurodegeneration

Year:

2013

Language:

english

File:

PDF, 174 KB

english, 2013

50

Intranasal immunization with 3A1 antibody reduced cerebral beta-amyloid multimers in 5XFAD mice

Chauhan, Neelima, Davis, Francesca, Xiao, Chun, O'Nuallain, Brian, Lemere, Cynthia

Journal:

Alzheimer's & Dementia

Year:

2013

Language:

english

File:

PDF, 281 KB

english, 2013

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